Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue

Limitations on the number of unique protein and DNA molecules that can be characterized microscopically in a single tissue specimen impede advances in understanding the biological basis of health and disease. Here we present a multiplexed fluorescence microscopy method (MxIF) for quantitative, singl...

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Bibliografiske detaljer
Main Authors: Gerdes, Michael J., Sevinsky, Christopher J., Sood, Anup, Adak, Sudeshna, Bello, Musodiq O., Bordwell, Alexander, Can, Ali, Corwin, Alex, Dinn, Sean, Filkins, Robert J., Hollman, Denise, Kamath, Vidya, Kaanumalle, Sireesha, Kenny, Kevin, Larsen, Melinda, Lazare, Michael, Li, Qing, Lowes, Christina, McCulloch, Colin C., McDonough, Elizabeth, Montalto, Michael C., Pang, Zhengyu, Rittscher, Jens, Santamaria-Pang, Alberto, Sarachan, Brion D., Seel, Maximilian L., Seppo, Antti, Shaikh, Kashan, Sui, Yunxia, Zhang, Jingyu, Ginty, Fiona
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718135/
https://ncbi.nlm.nih.gov/pubmed/23818604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300136110
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