Dysregulation of PAD4-mediated citrullination of nuclear GSK3β activates TGF-β signaling and induces epithelial-to-mesenchymal transition in breast cancer cells

Peptidylarginine deiminase 4 (PAD4) is a Ca(2+)-dependent enzyme that converts arginine and methylarginine residues to citrulline, with histone proteins being among its best-described substrates to date. However, the biological function of this posttranslational modification, either in histones or i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Stadler, Sonja C., Vincent, C. Theresa, Fedorov, Victor D., Patsialou, Antonia, Cherrington, Brian D., Wakshlag, Joseph J., Mohanan, Sunish, Zee, Barry M., Zhang, Xuesen, Garcia, Benjamin A., Condeelis, John S., Brown, Anthony M. C., Coonrod, Scott A., Allis, C. David
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718105/
https://ncbi.nlm.nih.gov/pubmed/23818587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308362110
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados