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The Cu regulon of the human fungal pathogen Cryptococcus neoformans H99: Cuf1 activates distinct genes in response to both Cu excess and deficiency

Cryptococcus neoformans is a human fungal pathogen that is the causative agent of cryptococcosis and fatal meningitis in immuno-compromised hosts. Recent studies suggest that copper (Cu) acquisition plays an important role in C. neoformans virulence, as mutants that lack Cuf1, which activates the Ct...

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Bibliografiske detaljer
Main Authors: Ding, Chen, Yin, Jun, Tovar, Edgar Mauricio Medina, Fitzpatrick, David A., Higgins, Desmond G., Thiele, Dennis J.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718005/
https://ncbi.nlm.nih.gov/pubmed/21819456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2011.07794.x
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