Glucose-Stimulated (45)Calcium Efflux from Isolated Rat Pancreatic Islets

Kinetics of (45)Ca efflux and insulin release were studied in collagenase-isolated rat islets during 2-h perifusions with calcium-depleted (0.05 mM) bicarbonate-phosphate buffer containing 2.2 mM glucose. Addition of glucose (16.7 mM) suppressed (45)Ca efflux by 30%. Removal of glucose caused an “of...

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Main Authors: Frankel, Barbara J., Imagawa, Walter T., O'Connor, Michael D. L., Lundquist, Ingmar, Kromhout, John A., Fanska, Rudolph E., Grodsky, Gerold M.
Format: Artigo
Jezik:Inglês
Izdano: 1978
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC371795/
https://ncbi.nlm.nih.gov/pubmed/357448
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