Direct Effects of Exendin-(9,39) and GLP-1-(9,36)amide on Insulin Action, β-Cell Function, and Glucose Metabolism in Nondiabetic Subjects

Exendin-(9,39) is a competitive antagonist of glucagon-like peptide-1 (GLP-1) at its receptor. However, it is unclear if it has direct and unique effects of its own. We tested the hypothesis that exendin-(9,39) and GLP-1-(9,36)amide have direct effects on hormone secretion and β-cell function as wel...

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Main Authors: Sathananthan, Matheni, Farrugia, Luca P., Miles, John M., Piccinini, Francesca, Dalla Man, Chiara, Zinsmeister, Alan R., Cobelli, Claudio, Rizza, Robert A., Vella, Adrian
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2013
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717878/
https://ncbi.nlm.nih.gov/pubmed/23545708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0140
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