Loss of Krüppel-Like Factor 3 (KLF3/BKLF) Leads to Upregulation of the Insulin-Sensitizing Factor Adipolin (FAM132A/CTRP12/C1qdc2)

Krüppel-like factor 3 (KLF3) is a transcriptional regulator that we have shown to be involved in the regulation of adipogenesis in vitro. Here, we report that KLF3-null mice are lean and protected from diet-induced obesity and glucose intolerance. On a chow diet, plasma levels of leptin are decrease...

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Main Authors: Bell-Anderson, Kim S., Funnell, Alister P., Williams, Helen, Mat Jusoh, Hanapi, Scully, Tiffany, Lim, Wooi F., Burdach, Jon G., Mak, Ka Sin, Knights, Alexander J., Hoy, Andrew J., Nicholas, Hannah R., Sainsbury, Amanda, Turner, Nigel, Pearson, Richard C., Crossley, Merlin
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2013
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717849/
https://ncbi.nlm.nih.gov/pubmed/23633521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1745
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