Species-specific transcription in mice carrying human chromosome 21

Homologous sets of transcription factors direct conserved tissue-specific gene expression, yet transcription factor binding events diverge rapidly between closely related species. We used hepatocytes from an aneuploid mouse strain carrying human chromosome 21 to determine on a chromosomal scale whet...

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Hlavní autoři: Wilson, Michael D., Barbosa-Morais, Nuno L., Schmidt, Dominic, Conboy, Caitlin M., Vanes, Lesley, Tybulewicz, Victor L. J., Fisher, Elizabeth M. C., Tavaré, Simon, Odom, Duncan T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717767/
https://ncbi.nlm.nih.gov/pubmed/18787134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1160930
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