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Structural and Biophysical Insights into the Role of CD4 and CD8 in T Cell Activation
T cell receptors (TCRs) recognize peptides presented by MHC molecules (pMHC) on an antigen-presenting cell (APC) to discriminate foreign from self-antigens and initiate adaptive immune responses. In addition, T cell activation generally requires binding of this same pMHC to a CD4 or CD8 co-receptor,...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3717711/ https://ncbi.nlm.nih.gov/pubmed/23885256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00206 |
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