Can cortical spreading depression activate central trigeminovascular neurons without peripheral input? Pitfalls of a new concept

Míreanna Comhchosúla

• Activation of central trigeminovascular neurons by cortical spreading depression
  le: Zhang, XiChun, et al.
  Foilsithe: (2011)
• Activation of Peripheral and Central Trigeminovascular Neurons by Seizure: Implications for Ictal and Postictal Headache
  le: Melo-Carrillo, Agustin, et al.
  Foilsithe: (2020)
• Cortical Spreading Depression Closes Paravascular Space and Impairs Glymphatic Flow: Implications for Migraine Headache
  le: Schain, Aaron J., et al.
  Foilsithe: (2017)
• Activation of the migraine pain pathway by cortical spreading depression: Do we need more evidence?
  le: Levy, Dan, et al.
  Foilsithe: (2011)
• Fremanezumab and its isotype slow propagation rate and shorten cortical recovery period but do not prevent occurrence of cortical spreading depression in rats with compromised blood brain barrier
  le: Melo-Carrillo, Agustin, et al.
  Foilsithe: (2020)