Hyposensitivity to Gamma-Aminobutyric Acid in the Ventral Tegmental Area During Alcohol Withdrawal: Reversal by Histone Deacetylase Inhibitors

Putative dopaminergic (pDAergic) ventral tegmental area (VTA) neurons have an important role in alcohol addiction. Acute ethanol increases the activity of pDAergic neurons, and withdrawal from repeated ethanol administration produces a decreased sensitivity of pDAergic VTA neurons to GABA. Recent st...

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Detalhes bibliográficos
Main Authors: Arora, Devinder S, Nimitvilai, Sudarat, Teppen, Tara L, McElvain, Maureen A, Sakharkar, Amul J, You, Chang, Pandey, Subhash C, Brodie, Mark S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717553/
https://ncbi.nlm.nih.gov/pubmed/23474591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.65
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