Φορτώνει......
Blockade of Tau Hyperphosphorylation and Aβ(1–42) Generation by the Aminotetrahydrofuran Derivative ANAVEX2-73, a Mixed Muscarinic and σ(1) Receptor Agonist, in a Nontransgenic Mouse Model of Alzheimer's Disease
The main objective of the present study was to establish whether the mixed σ(1)/muscarinic ligand ANAVEX2-73, shown to be neuroprotective in Alzheimer's disease (AD) models in vivo and currently in clinical phase I/IIa, could have the ability to reduce the appearance of hyperphosphorylated Tau...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3717544/ https://ncbi.nlm.nih.gov/pubmed/23493042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.70 |
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