5-HT(2C) Receptor Agonist Anorectic Efficacy Potentiated by 5-HT(1B) Receptor Agonist Coapplication: An Effect Mediated via Increased Proportion of Pro-Opiomelanocortin Neurons Activated

An essential component of the neural network regulating ingestive behavior is the brain 5-hydroxytryptamine2C receptor (5-HT(2C)R), agonists of which suppress food intake and were recently approved for obesity treatment by the US Food and Drug Administration. 5-HT(2C)R-regulated appetite is mediated...

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Autors principals: Doslikova, Barbora, Garfield, Alastair S., Shaw, Jill, Evans, Mark L., Burdakov, Denis, Billups, Brian, Heisler, Lora K.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2013
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717514/
https://ncbi.nlm.nih.gov/pubmed/23739976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4326-12.2013
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