Antagonist-Elicited Cannabis Withdrawal in Humans

Cannabinoid CB1 receptor antagonists have potential therapeutic benefits, but antagonist-elicited cannabis withdrawal has not been reported in humans. Ten male daily cannabis smokers received 8 days of increasingly frequent 20-mg oral Δ(9)-tetrahydrocannabinol (THC) dosages (40–120 mg/d) around-the-...

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Detalhes bibliográficos
Main Authors: Gorelick, David A., Goodwin, Robert S., Schwilke, Eugene, Schwope, David M., Darwin, William D., Kelly, Deanna L., McMahon, Robert P., Liu, Fang, Ortemann-Renon, Catherine, Bonnet, Denis, Huestis, Marilyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717344/
https://ncbi.nlm.nih.gov/pubmed/21869692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JCP.0b013e31822befc1
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