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Platelets and Microtubules: EFFECT OF COLCHICINE AND D(2)O ON PLATELET AGGREGATION AND RELEASE INDUCED BY CALCIUM IONOPHORE A23187

We examined the role of microtubules in platelet aggregation and secretion (release reaction) induced by the calcium ionophore A23187 (0.8-5 μM). At these concentrations, platelet aggregation was preceded by a lag period of ∼1 min. Colchicine (an agent that disrupts microtubule assembly-disassembly)...

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Detalhes bibliográficos
Main Authors: Menche, D., Israel, A., Karpatkin, S.
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC371709/
https://ncbi.nlm.nih.gov/pubmed/6772671
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