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Mitogenic Properties of a Calcium Ionophore, A23187

A23187 is a carboxylic antibiotic that selectively transfers calcium, magnesium, and other divalent cations across biologic membranes. This ionophore was found to produce morphologic blast transformation, DNA synthesis, and mitosis in human lymphocytes. Several hours of ionophore-cell contact were n...

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Autors principals: Luckasen, John R., White, James G., Kersey, John H.
Format: Artigo
Idioma:Inglês
Publicat: 1974
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC434045/
https://ncbi.nlm.nih.gov/pubmed/4531040
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