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Catch bond-like kinetics of helix cracking: Network analysis by molecular dynamics and Milestoning

The first events of unfolding of secondary structure under load are considered with Molecular Dynamics simulations and Milestoning analysis of a long helix (126 amino acids). The Mean First Passage Time is a non-monotonic function of the applied load with a maximum of 3.6 ns at about 20 pN. Network...

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Detaylı Bibliyografya
Asıl Yazarlar: Kreuzer, Steven M., Elber, Ron
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: AIP Publishing LLC 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716791/
https://ncbi.nlm.nih.gov/pubmed/24089714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4811366
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