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Early Events in Helix Unfolding Under External Forces: A Milestoning Analysis

Initial events of helix breakage as a function of load are considered using Molecular Dynamics simulations and Milestoning analysis. A helix length of ~100 amino acids is considered as a model for typical helices found in molecular machines and as a model that minimizes end effects for early events...

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Detalhes bibliográficos
Main Authors: Kreuzer, Steven M, Elber, Ron, Moon, Tess J
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406243/
https://ncbi.nlm.nih.gov/pubmed/22471347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp300788e
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