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The S100A8/A9 complex reduces CTLA4 expression by immature myeloid cells: Implications for pancreatic cancer-driven immunosuppression

An expansion of different myeloid derived suppressive cell (MDSC) subsets can be detected in the blood and secondary lymphoid organs of early and advanced pancreatic ductal adenocarcinoma (PDAC) patients. Double negative (CD14(−)HLA-DR(−)) MDSCs are frequently induced by PDACs. In addition, by relea...

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Detalhes bibliográficos
Main Authors: Basso, Daniela, Fogar, Paola, Plebani, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716738/
https://ncbi.nlm.nih.gov/pubmed/23894703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24441
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