Static Mechanical Stress Induces Apoptosis in Rat Endplate Chondrocytes through MAPK and Mitochondria-Dependent Caspase Activation Signaling Pathways

Mechanical stress has detrimental effects on cartilaginous endplate chondrocytes due to apoptosis in vivo and in vitro. In this study, we investigated the possible apoptosis signaling pathways induced by mechanical stress in cultured rat cervical endplate chondrocytes. Static mechanical load signifi...

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Autori principali: Kong, Dechao, Zheng, Tiansheng, Zhang, Ming, Wang, Daode, Du, Shihao, Li, Xiang, Fang, Jiahu, Cao, Xiaojian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716647/
https://ncbi.nlm.nih.gov/pubmed/23894471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069403
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