Static Mechanical Stress Induces Apoptosis in Rat Endplate Chondrocytes through MAPK and Mitochondria-Dependent Caspase Activation Signaling Pathways

Mechanical stress has detrimental effects on cartilaginous endplate chondrocytes due to apoptosis in vivo and in vitro. In this study, we investigated the possible apoptosis signaling pathways induced by mechanical stress in cultured rat cervical endplate chondrocytes. Static mechanical load signifi...

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Autors principals: Kong, Dechao, Zheng, Tiansheng, Zhang, Ming, Wang, Daode, Du, Shihao, Li, Xiang, Fang, Jiahu, Cao, Xiaojian
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716647/
https://ncbi.nlm.nih.gov/pubmed/23894471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069403
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