Surface α-Enolase Promotes Extracellular Matrix Degradation and Tumor Metastasis and Represents a New Therapeutic Target

In previous research, we found α-enolase to be inversely correlated with progression-free and overall survival in lung cancer patients and detected α-enolase on the surface of lung cancer cells. Based on these findings, we hypothesized that surface α-enolase has a significant role in cancer metastas...

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Main Authors: Hsiao, Kuan-Chung, Shih, Neng-Yao, Fang, Hsun-Lang, Huang, Tze-Sing, Kuo, Ching-Chuan, Chu, Pei-Yi, Hung, Yi-Mei, Chou, Shao-Wen, Yang, Yi-Yuan, Chang, Gee-Chen, Liu, Ko-Jiunn
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716638/
https://ncbi.nlm.nih.gov/pubmed/23894455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069354
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