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Elevated Expression of Lumican in Lung Cancer Cells Promotes Bone Metastasis through an Autocrine Regulatory Mechanism

Background: The microarray analysis of whole-genome expression indicated that the gene encoding the protein lumican, which is associated with extracellular matrix (ECM) interaction, was highly expressed in osteotropic lung cancer cell lines with an enhanced capacity of bone metastasis. Methods: The...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Hsiao, Kuan-Chung, Chu, Pei-Yi, Chang, Gee-Chen, Liu, Ko-Jiunn
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016828/
https://ncbi.nlm.nih.gov/pubmed/31963522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010233
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