Tolerogenic Vaccination Reduced Effector Memory CD4 T Cells and Induced Effector Memory Treg Cells for Type I Diabetes Treatment

BACKGROUND: Vaccination could induce immune tolerance and protected NOD mice from the development of type I diabetes (T1D). We previously demonstrated that insulin peptide (B9-23) combined with dexamethasone (DEX) stimulated the expansion of antigen specific regulatory T (Treg) cells which in turn e...

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Detalhes bibliográficos
Main Authors: Zhang, Jingyao, Gao, Wenjuan, Yang, Xu, Kang, Jingjing, Zhang, Yongliang, Guo, Qirui, Hu, Yanxin, Xia, Guoliang, Kang, Youmin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716605/
https://ncbi.nlm.nih.gov/pubmed/23894591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070056
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