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Treg cell resistance to apoptosis in DNA vaccination for experimental autoimmune encephalomyelitis treatment.

BACKGROUND: Regulatory T (Treg) cells can be induced with DNA vaccinations and protect mice from the development of experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis (MS). Tacrolimus (FK506) has been shown to have functions on inducing immunosuppression and augment...

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Autori principali: Youmin Kang, Yuhan Sun, Jingyao Zhang, Wenjuan Gao, Jingjing Kang, Yongqiang Wang, Bin Wang, Guoliang Xia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2012-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3498204?pdf=render
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