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Synthetic lipid membrane channels formed by designed DNA nanostructures
We created nanometer-scale transmembrane channels in lipid bilayers using self-assembled DNA-based nanostructures. Scaffolded DNA origami was used to create a stem that penetrates and spans a lipid membrane, and a barrel-shaped cap that adheres to the membrane in part via 26 cholesterol moieties. In...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3716461/ https://ncbi.nlm.nih.gov/pubmed/23161995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1225624 |
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