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Synthetic lipid membrane channels formed by designed DNA nanostructures
We created nanometer-scale transmembrane channels in lipid bilayers using self-assembled DNA-based nanostructures. Scaffolded DNA origami was used to create a stem that penetrates and spans a lipid membrane, and a barrel-shaped cap that adheres to the membrane in part via 26 cholesterol moieties. In...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3716461/ https://ncbi.nlm.nih.gov/pubmed/23161995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1225624 |
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