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Tissue Distribution, Ontogeny, and Chemical Induction of Aldo-Keto Reductases in Mice

Aldo-keto reductases (Akrs) are a conserved group of NADPH-dependent oxido-reductase enzymes. This study provides a comprehensive examination of the tissue distribution of the 16 substrate-metabolizing Akrs in mice, their expression during development, and whether they are altered by chemicals that...

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Detalhes bibliográficos
Main Authors: Pratt-Hyatt, Matthew, Lickteig, Andrew J., Klaassen, Curtis D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716307/
https://ncbi.nlm.nih.gov/pubmed/23660342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.113.051904
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