Semen-Derived Enhancer of Viral Infection (SEVI) Binds Bacteria, Enhances Bacterial Phagocytosis by Macrophages, and Can Protect against Vaginal Infection by a Sexually Transmitted Bacterial Pathogen

The semen-derived enhancer of viral infection (SEVI) is a positively charged amyloid fibril that is derived from a self-assembling proteolytic cleavage fragment of prostatic acid phosphatase (PAP(248-286)). SEVI efficiently facilitates HIV-1 infection in vitro, but its normal physiologic function re...

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Detalhes bibliográficos
Main Authors: Easterhoff, David, Ontiveros, Fernando, Brooks, Lauren R., Kim, Yoel, Ross, Brittany, Silva, Jharon N., Olsen, Joanna S., Feng, Changyong, Hardy, Dwight J., Dunman, Paul M., Dewhurst, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716189/
https://ncbi.nlm.nih.gov/pubmed/23507280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02464-12
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