A liaF Codon Deletion Abolishes Daptomycin Bactericidal Activity against Vancomycin-Resistant Enterococcus faecalis

The genetic bases for antibiotic tolerance are obscure. Daptomycin (DAP) is a lipopeptide antibiotic with bactericidal activity against enterococci. Using time-kill assays, we provide evidence for the first time that a deletion of isoleucine in position 177 of LiaF, a member of the three-component r...

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Detaylı Bibliyografya
Asıl Yazarlar: Munita, Jose M., Tran, Truc T., Diaz, Lorena, Panesso, Diana, Reyes, Jinnethe, Murray, Barbara E., Arias, Cesar A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Mechanisms of Resistance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716119/
https://ncbi.nlm.nih.gov/pubmed/23507277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00021-13
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