A Pragmatic Approach to HIV-1 Drug Resistance Determination in Resource-Limited Settings by Use of a Novel Genotyping Assay Targeting the Reverse Transcriptase-Encoding Region Only

In resource-limited settings (RLS), reverse transcriptase (RT) inhibitors form the backbone of first-line treatment regimens. We have developed a simplified HIV-1 drug resistance genotyping assay targeting the region of RT harboring all major RT inhibitor resistance mutation positions, thus providin...

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Main Authors: Aitken, Susan C., Bronze, Michelle, Wallis, Carole L., Stuyver, Lieven, Steegen, Kim, Balinda, Sheila, Kityo, Cissy, Stevens, Wendy, Rinke de Wit, Tobias F., Schuurman, Rob
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Virology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716103/
https://ncbi.nlm.nih.gov/pubmed/23536405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00118-13
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