HIV-1 Phenotypic Reverse Transcriptase Inhibitor Drug Resistance Test Interpretation Is Not Dependent on the Subtype of the Virus Backbone

To date, the majority of HIV-1 phenotypic resistance testing has been performed with subtype B virus backbones (e.g. HXB2). However, the relevance of using this backbone to determine resistance in non-subtype B HIV-1 viruses still needs to be assessed. From 114 HIV-1 subtype C clinical samples (36 A...

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Detalhes bibliográficos
Main Authors: Bronze, Michelle, Steegen, Kim, Wallis, Carole L., De Wolf, Hans, Papathanasopoulos, Maria A., Van Houtte, Margriet, Stevens, Wendy S., de Wit, Tobias Rinke, Stuyver, Lieven J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322145/
https://ncbi.nlm.nih.gov/pubmed/22496845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034708
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