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Increased B7-H1 expression on dendritic cells correlates with PD-1 expression on T cells in SIV-infected macaques and may contribute to T cell dysfunction and disease progression
Suppression of dendritic cell function in HIV-1 infection is thought to contribute to inhibition of immune responses and disease progression, but the mechanism of this suppression remains undetermined. Using the rhesus macaque model, we show B7-H1 (PD-L1) is expressed on lymphoid and mucosal dendrit...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3716008/ https://ncbi.nlm.nih.gov/pubmed/21059890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001642 |
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