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Monitoring α4β7 integrin expression on circulating CD4+ T cells as a surrogate marker for tracking intestinal CD4+ T cell loss in SIV infection

Intestinal CD4+ T cells are rapidly and profoundly depleted in HIV-infected patients and SIV-infected macaques. However, monitoring intestinal cells in humans is difficult, and identifying surrogate markers in the blood, which correlate with loss or restoration of intestinal CD4+ T cells could be he...

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Hlavní autoři: Wang, Xiaolei, Xu, Huanbin, Gill, Amy F., Pahar, Bapi, Kempf, Doty, Rasmussen, Terri, Lackner, Andrew A., Veazey, Ronald S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702381/
https://ncbi.nlm.nih.gov/pubmed/19710637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2009.104
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