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Total Synthesis of Aplyronine C
[Image: see text] A highly stereocontrolled total synthesis of the cytotoxic marine macrolide aplyronine C is described. The route exploits aldol methodology to install the requisite stereochemistry and features a crucial boron-mediated aldol coupling of an N-vinylformamide-bearing methyl ketone wit...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Chemical Society
2013
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3715889/ https://ncbi.nlm.nih.gov/pubmed/23730909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol401327r |
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