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Ral mediates activity-dependent growth of postsynaptic membranes via recruitment of the exocyst
Remodelling neuronal connections by synaptic activity requires membrane trafficking. We present evidence for a signalling pathway by which synaptic activity and its consequent Ca(2+) influx activate the small GTPase Ral and thereby recruit exocyst proteins to postsynaptic zones. In accord with the a...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
European Molecular Biology Organization
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3715865/ https://ncbi.nlm.nih.gov/pubmed/23812009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.147 |
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