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Ral mediates activity-dependent growth of postsynaptic membranes via recruitment of the exocyst

Remodelling neuronal connections by synaptic activity requires membrane trafficking. We present evidence for a signalling pathway by which synaptic activity and its consequent Ca(2+) influx activate the small GTPase Ral and thereby recruit exocyst proteins to postsynaptic zones. In accord with the a...

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Détails bibliographiques
Auteurs principaux: Teodoro, Rita O, Pekkurnaz, Gulçin, Nasser, Abdullah, Higashi-Kovtun, Misao E, Balakireva, Maria, McLachlan, Ian G, Camonis, Jacques, Schwarz, Thomas L
Format: Artigo
Langue:Inglês
Publié: European Molecular Biology Organization 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715865/
https://ncbi.nlm.nih.gov/pubmed/23812009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.147
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