Ultra-deep profiling of alternatively spliced Drosophila Dscam isoforms by circularization-assisted multi-segment sequencing

The Drosophila melanogaster gene Dscam (Down syndrome cell adhesion molecule) can generate thousands of different ectodomains via mutual exclusive splicing of three large exon clusters. The isoform diversity plays a profound role in both neuronal wiring and pathogen recognition. However, the isoform...

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Main Authors: Sun, Wei, You, Xintian, Gogol-Döring, Andreas, He, Haihuai, Kise, Yoshiaki, Sohn, Madlen, Chen, Tao, Klebes, Ansgar, Schmucker, Dietmar, Chen, Wei
Formato: Artigo
Idioma:Inglês
Publicado: European Molecular Biology Organization 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715862/
https://ncbi.nlm.nih.gov/pubmed/23792425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.144
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