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Effect of Calcium on Superoxide Production by Phagocytic Vesicles from Rabbit Alveolar Macrophages

Phagocytic vesicles from rabbit lung macrophages produced superoxide in the presence of NADH or NADPH. At 37°C, these vesicles generated 51±7.8 nmol O(2)(−)/min per mg protein in the presence of 0.5 mM NADPH. The apparent K(m) for NADPH and NADH (66 and 266 μM, respectively), the pH optimum for the...

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Pubblicato in:J Clin Invest
Autori principali: Lew, P. Daniel, Stossel, Thomas P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1981
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371565/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6256409/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110000
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