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Effect of Calcium on Superoxide Production by Phagocytic Vesicles from Rabbit Alveolar Macrophages

Phagocytic vesicles from rabbit lung macrophages produced superoxide in the presence of NADH or NADPH. At 37°C, these vesicles generated 51±7.8 nmol O(2)(−)/min per mg protein in the presence of 0.5 mM NADPH. The apparent K(m) for NADPH and NADH (66 and 266 μM, respectively), the pH optimum for the...

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Detalhes bibliográficos
Main Authors: Lew, P. Daniel, Stossel, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC371565/
https://ncbi.nlm.nih.gov/pubmed/6256409
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