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Lipoxygenation of arachidonic acid as a source of polymorphonuclear leukocyte chemotactic factors in synovial fluid and tissue in rheumatoid arthritis and spondyloarthritis.

The predominant lipoxygenase products of arachidonic acid were extracted and purified from synovial fluid and sonicates of synovial tissue of patients with rheumatoid arthritis (RA), spondyloarthritis (SA), or a noninflammatory arthropathy (NIA). The concentration of 5(S),12(R)-dihydroxy-6,8,10-(tra...

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Опубликовано в::J Clin Invest
Главные авторы: Klickstein, L B, Shapleigh, C, Goetzl, E J
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1980
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371556/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6253525/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109947
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