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Schedule-dependent cytotoxicity of methotrexate and 5-fluorouracil in human colon and breast tumor cell lines.

The effect of sequential methotrexate and 5-fluorouracil on the clonal growth of the human colon adenocarcinoma cell, HCT-8, and the hormone-dependent human breast carcinoma cell, 47-DN, was examined. In both cell lines, when 5-fluorouracil was given during the last 6 h of a 24 h methotrexate exposu...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Benz, C, Schoenberg, M, Choti, M, Cadman, E
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1980
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371555/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7430346/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109946
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