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Less cytotoxicity to combination therapy of 5-fluorouracil and cisplatin than 5-fluorouracil alone in human colon cancer cell lines

AIM: Our previous studies showed increased sensitivity to 5-FU in colon cancer cell lines with microsatellite instability, and considered that mutations of TGFβ-R II, IGF IIR, RIZ gene might enhance the potentials of cell growth and proliferation, which increased the sensitivity to 5-FU. Here we com...

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Publicat a:World J Gastroenterol
Autors principals: Chen, Xiu-Xu, Lai, Mao-De, Zhang, Yong-Liang, Huang, Qiong
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Inc 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656572/
https://ncbi.nlm.nih.gov/pubmed/12378627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v8.i5.841
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