Normalizing RNA-Sequencing Data by Modeling Hidden Covariates with Prior Knowledge

Transcriptomic assays that measure expression levels are widely used to study the manifestation of environmental or genetic variations in cellular processes. RNA-sequencing in particular has the potential to considerably improve such understanding because of its capacity to assay the entire transcri...

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Autors principals: Mostafavi, Sara, Battle, Alexis, Zhu, Xiaowei, Urban, Alexander E., Levinson, Douglas, Montgomery, Stephen B., Koller, Daphne
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715474/
https://ncbi.nlm.nih.gov/pubmed/23874524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068141
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