Normalizing RNA-Sequencing Data by Modeling Hidden Covariates with Prior Knowledge

Transcriptomic assays that measure expression levels are widely used to study the manifestation of environmental or genetic variations in cellular processes. RNA-sequencing in particular has the potential to considerably improve such understanding because of its capacity to assay the entire transcri...

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Detalhes bibliográficos
Main Authors: Mostafavi, Sara, Battle, Alexis, Zhu, Xiaowei, Urban, Alexander E., Levinson, Douglas, Montgomery, Stephen B., Koller, Daphne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715474/
https://ncbi.nlm.nih.gov/pubmed/23874524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068141
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