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Binding, internalization, and lysosomal association of 125I-glucagon in isolated rat hepatocytes. A quantitative electron microscope autoradiographic study.

When 125I-glucagon is incubated with freshly isolated rat hepatocytes and studied by quantitative electron microscope autoradiography, the labeled material localizes to the plasma membrane of the cell at early times of incubation of 20 degrees C; at later times of incubation at 20 degrees C, there i...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Barazzone, P, Gorden, P, Carpentier, J L, Orci, L, Freychet, P, Canivet, B
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1980
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371546/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7430344/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109937
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