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Disease-Related Growth Factor and Embryonic Signaling Pathways Modulate an Enhancer of TCF21 Expression at the 6q23.2 Coronary Heart Disease Locus

Coronary heart disease (CHD) is the leading cause of mortality in both developed and developing countries worldwide. Genome-wide association studies (GWAS) have now identified 46 independent susceptibility loci for CHD, however, the biological and disease-relevant mechanisms for these associations r...

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Detaylı Bibliyografya
Asıl Yazarlar: Miller, Clint L., Anderson, D. Ryan, Kundu, Ramendra K., Raiesdana, Azad, Nürnberg, Sylvia T., Diaz, Roxanne, Cheng, Karen, Leeper, Nicholas J., Chen, Chung-Hsing, Chang, I-Shou, Schadt, Eric E., Hsiung, Chao Agnes, Assimes, Themistocles L., Quertermous, Thomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715442/
https://ncbi.nlm.nih.gov/pubmed/23874238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003652
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