Disease-Related Growth Factor and Embryonic Signaling Pathways Modulate an Enhancer of TCF21 Expression at the 6q23.2 Coronary Heart Disease Locus

Coronary heart disease (CHD) is the leading cause of mortality in both developed and developing countries worldwide. Genome-wide association studies (GWAS) have now identified 46 independent susceptibility loci for CHD, however, the biological and disease-relevant mechanisms for these associations r...

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Bibliografski detalji
Glavni autori: Miller, Clint L., Anderson, D. Ryan, Kundu, Ramendra K., Raiesdana, Azad, Nürnberg, Sylvia T., Diaz, Roxanne, Cheng, Karen, Leeper, Nicholas J., Chen, Chung-Hsing, Chang, I-Shou, Schadt, Eric E., Hsiung, Chao Agnes, Assimes, Themistocles L., Quertermous, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715442/
https://ncbi.nlm.nih.gov/pubmed/23874238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003652
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