Disease-Related Growth Factor and Embryonic Signaling Pathways Modulate an Enhancer of TCF21 Expression at the 6q23.2 Coronary Heart Disease Locus

Coronary heart disease (CHD) is the leading cause of mortality in both developed and developing countries worldwide. Genome-wide association studies (GWAS) have now identified 46 independent susceptibility loci for CHD, however, the biological and disease-relevant mechanisms for these associations r...

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Autores principales: Miller, Clint L., Anderson, D. Ryan, Kundu, Ramendra K., Raiesdana, Azad, Nürnberg, Sylvia T., Diaz, Roxanne, Cheng, Karen, Leeper, Nicholas J., Chen, Chung-Hsing, Chang, I-Shou, Schadt, Eric E., Hsiung, Chao Agnes, Assimes, Themistocles L., Quertermous, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715442/
https://ncbi.nlm.nih.gov/pubmed/23874238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003652
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