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The Role of Multiple Marks in Epigenetic Silencing and the Emergence of a Stable Bivalent Chromatin State
We introduce and analyze a minimal model of epigenetic silencing in budding yeast, built upon known biomolecular interactions in the system. Doing so, we identify the epigenetic marks essential for the bistability of epigenetic states. The model explicitly incorporates two key chromatin marks, namel...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3715441/ https://ncbi.nlm.nih.gov/pubmed/23874171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003121 |
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