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Improving Pharmacokinetic-Pharmacodynamic Modeling to Investigate Anti-Infective Chemotherapy with Application to the Current Generation of Antimalarial Drugs

Mechanism-based pharmacokinetic-pharmacodynamic (PK/PD) modelling is the standard computational technique for simulating drug treatment of infectious diseases with the potential to enhance our understanding of drug treatment outcomes, drug deployment strategies, and dosing regimens. Standard methodo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kay, Katherine, Hastings, Ian M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715401/
https://ncbi.nlm.nih.gov/pubmed/23874190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003151
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