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Caffeine induces CYP1A2 expression in rat hepatocytes but not in human hepatocytes
Caffeine is the active constituent in coffee. Continual consumption of caffeine can lead to an attenuated response also known as tolerance. Results from rat studies have shown that caffeine is an inducer of CYP1A2, the enzyme responsible for caffeine’s metabolism. This suggests that CYP1A2 induction...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3715142/ https://ncbi.nlm.nih.gov/pubmed/23167901 |
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