A Eukaryotic Specific Transmembrane Segment is Required for Tetramerization in AMPA Receptors

Most fast excitatory synaptic transmission in the nervous system is mediated by glutamate acting through ionotropic glutamate receptors (iGluRs). iGluRs (AMPA, kainate, and NMDA receptor subtypes) are tetrameric assemblies, formed as a dimer of dimers. Still, the mechanism underlying tetramerization...

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Autors principals: Salussolia, Catherine L., Gan, Quan, Kazi, Rashek, Singh, Puja, Allopenna, Janet, Furukawa, Hiro, Wollmuth, Lonnie P.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2013
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714855/
https://ncbi.nlm.nih.gov/pubmed/23739980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2626-12.2013
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